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AGER-Mediated Lipid Peroxidation Drives Caspase-11 Inflammasome Activation in Sepsis
Inflammasome activation can trigger an inflammatory and innate immune response through the release of cytokines and induction of pyroptosis. A dysfunctional inflammasome has been implicated in the development of human pathologies, including sepsis and septic shock. Here, we show that advanced glycos...
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| Vydáno v: | Front Immunol |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6694796/ https://ncbi.nlm.nih.gov/pubmed/31440260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01904 |
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