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Inactivation of Sox9 in fibroblasts reduces cardiac fibrosis and inflammation
Fibrotic scarring drives the progression of heart failure after myocardial infarction (MI). Therefore, the development of specific treatment regimens to counteract fibrosis is of high clinical relevance. The transcription factor sex-determining region Y box 9 (SOX9) functions as an important regulat...
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| Veröffentlicht in: | JCI Insight |
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| Hauptverfasser: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6693887/ https://ncbi.nlm.nih.gov/pubmed/31310588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126721 |
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