GATA6 Promotes Angiogenic Function and Survival in Endothelial Cells by Suppression of Autocrine Transforming Growth Factor β/Activin Receptor-like Kinase 5 Signaling

Understanding the transcriptional regulation of angiogenesis could lead to the identification of novel therapeutic targets. We showed here that the transcription factor GATA6 is expressed in different human primary endothelial cells as well as in vascular endothelial cells of mice in vivo. Activatio...

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Main Authors: Froese, Natali, Kattih, Badder, Breitbart, Astrid, Grund, Andrea, Geffers, Robert, Molkentin, Jeffery D., Kispert, Andreas, Wollert, Kai C., Drexler, Helmut, Heineke, Joerg
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037681/
https://ncbi.nlm.nih.gov/pubmed/21127043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.176925
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