Rhodium-Catalyzed Asymmetric Hydroamination of Allyl Amines

A Rh-catalyzed enantioselective hydroamination of allylamines using a chiral BIPHEP-type ligand is reported. Enantioenriched 1,2-diamines are formed in good yields and with excellent enantioselectivities. A diverse array of nucleophiles and amine directing groups are demonstrated, including deprotec...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Vanable, Evan P., Kennemur, Jennifer L., Joyce, Leo A., Ruck, Rebecca T., Schultz, Danielle M., Hull, Kami L.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693864/
https://ncbi.nlm.nih.gov/pubmed/30614700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b09811
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