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Asymmetric synthesis of γ-branched amines via rhodium-catalyzed reductive amination

Amines bearing γ-stereocenters are highly important structural motifs in many biologically active compounds. However, reported enantioselective syntheses of these molecules are indirect and often require multiple steps. Herein, we report a general asymmetric route for the one-pot synthesis of chiral...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Wu, Zhao, Laffoon, Summer D., Hull, Kami L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864842/
https://ncbi.nlm.nih.gov/pubmed/29567989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03535-y
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