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Asymmetric Synthesis of α-Branched Amines via Rh(III)-Catalyzed C–H Bond Functionalization

[Image: see text] The first asymmetric intermolecular addition of non-acidic C–H bonds to imines is reported. The use of the activating N-perfluorobutanesulfinyl imine substituent is essential for achieving sufficient reactivity and provides outstanding diastereoselectivity (>98:2 dr). Straightfo...

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Detalhes bibliográficos
Principais autores: Wangweerawong, Apiwat, Bergman, Robert G., Ellman, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105057/
https://ncbi.nlm.nih.gov/pubmed/24901217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5033452
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