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Triazoloquinazolines as a new class of potent α-glucosidase inhibitors: in vitro evaluation and docking study

Previously, we synthesized triazoloquinazolines 1–14 and characterized their structure. In this study, we aimed to evaluate the in vitro activity of the targets 1–14 as α-glucosidase inhibitors using α-glucosidase enzyme from Saccharomyces cerevisiae type 1. Among the tested compounds, triazoloquina...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Abuelizz, Hatem A., Anouar, El Hassane, Ahmad, Rohaya, Azman, Nor Izzati Iwana Nor, Marzouk, Mohamed, Al-Salahi, Rashad
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693780/
https://ncbi.nlm.nih.gov/pubmed/31412050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220379
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