Synthesis, biological activity and molecular docking of new tricyclic series as α-glucosidase inhibitors

Diabetes is an emerging metabolic disorder. α-Glucosidase inhibitors, such as acarbose, delay the hydrolysis of carbohydrates by interfering with the digestive enzymes. This action decreases the glucose absorption and the postprandial glucose level. We have synthesized 25 tricyclic 2-phenoxypyrido[3...

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Vydáno v:BMC Chem
Hlavní autoři: Abuelizz, Hatem A., Iwana, Nor Azman N. I., Ahmad, Rohaya, Anouar, El-Hassane, Marzouk, Mohamed, Al-Salahi, Rashad
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661812/
https://ncbi.nlm.nih.gov/pubmed/31384800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-019-0560-4
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