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Synthesis, biological activity and molecular docking of new tricyclic series as α-glucosidase inhibitors

Diabetes is an emerging metabolic disorder. α-Glucosidase inhibitors, such as acarbose, delay the hydrolysis of carbohydrates by interfering with the digestive enzymes. This action decreases the glucose absorption and the postprandial glucose level. We have synthesized 25 tricyclic 2-phenoxypyrido[3...

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Détails bibliographiques
Publié dans:BMC Chem
Auteurs principaux: Abuelizz, Hatem A., Iwana, Nor Azman N. I., Ahmad, Rohaya, Anouar, El-Hassane, Marzouk, Mohamed, Al-Salahi, Rashad
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661812/
https://ncbi.nlm.nih.gov/pubmed/31384800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-019-0560-4
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