Triazoloquinazolines as a new class of potent α-glucosidase inhibitors: in vitro evaluation and docking study

Previously, we synthesized triazoloquinazolines 1–14 and characterized their structure. In this study, we aimed to evaluate the in vitro activity of the targets 1–14 as α-glucosidase inhibitors using α-glucosidase enzyme from Saccharomyces cerevisiae type 1. Among the tested compounds, triazoloquina...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Abuelizz, Hatem A., Anouar, El Hassane, Ahmad, Rohaya, Azman, Nor Izzati Iwana Nor, Marzouk, Mohamed, Al-Salahi, Rashad
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693780/
https://ncbi.nlm.nih.gov/pubmed/31412050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220379
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