Molecular Docking and Anticonvulsant Activity of Newly Synthesized Quinazoline Derivatives

A new series of quinazoline-4(3H)-ones are evaluated for anticonvulsant activity. After intraperitoneal (ip) injection to albino mice at a dose of 100 mg/kg body weight, synthesized quinazolin-4(3H)-ones (1–24) were examined in the maximal electroshock (MES) induced seizures and subcutaneous pentyle...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Abuelizz, Hatem A., El Dib, Rabab, Marzouk, Mohamed, Anouar, El-Hassane, Maklad, Yousreya A., Attia, Hanan N., Al-Salahi, Rashad
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152033/
https://ncbi.nlm.nih.gov/pubmed/28665338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22071094
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