The dynamics of FTO binding and demethylation from the m(6)A motifs

N(6)-methyladenosine (m(6)A) is considered as a reversible RNA modification occurring more frequently on the GAC than AAC context in vivo, which regulates post-transcriptional gene expression in mammalian cells. m(6)A ‘writers’ METTL3 and METTL14 demonstrate a strong preference for binding AC-contai...

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Vydáno v:RNA Biol
Hlavní autoři: Li, Yixing, Wu, Kejing, Quan, Weili, Yu, Lin, Chen, Shuang, Cheng, Chao, Wu, Qijia, Zhao, Shuhong, Zhang, Yi, Zhou, Lei
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693534/
https://ncbi.nlm.nih.gov/pubmed/31149892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1621120
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