CRISPR-READI: Efficient generation of knock-in mice by CRISPR RNP Electroporation and AAV Donor Infection

Genetically engineered mouse models harboring large sequence insertions or modifications are critical for a wide range of applications including endogenous gene tagging, conditional knockout, site-specific transgene insertion, and gene replacement; however, existing methods to generate such animals...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Chen, Sean, Sun, Sabrina, Moonen, Dewi, Lee, Clancy, Yiu-Fai Lee, Angus, Schaffer, David V., He, Lin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693498/
https://ncbi.nlm.nih.gov/pubmed/31242412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.05.103
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