CRISPR-READI: Efficient Generation of Knockin Mice by CRISPR RNP Electroporation and AAV Donor Infection

Summary: Genetically engineered mouse models harboring large sequence insertions or modifications are critical for a wide range of applications including endogenous gene tagging, conditional knockout, site-specific transgene insertion, and gene replacement; however, existing methods to generate such...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Sean Chen, Sabrina Sun, Dewi Moonen, Clancy Lee, Angus Yiu-Fai Lee, David V. Schaffer, Lin He
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2019-06-01
श्रृंखला:Cell Reports
ऑनलाइन पहुंच:http://www.sciencedirect.com/science/article/pii/S2211124719307429
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