Continuous PTH in Male Mice Causes Bone Loss Because It Induces Serum Amyloid A

Increased bone resorption is considered to explain why intermittent PTH is anabolic for bone but continuous PTH is catabolic. However, when cyclooxygenase-2 (COX2) is absent in mice, continuous PTH becomes anabolic without decreased resorption. In murine bone marrow stromal cells (BMSCs), serum amyl...

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Pubblicato in:Endocrinology
Autori principali: Choudhary, Shilpa, Santone, Elizabeth, Yee, Sui-Pok, Lorenzo, Joseph, Adams, Douglas J, Goetjen, Alexandra, McCarthy, Mary Beth, Mazzocca, Augustus D, Pilbeam, Carol
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2018
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692876/
https://ncbi.nlm.nih.gov/pubmed/29757436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00265
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