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Prostaglandin-mediated inhibition of PTH-stimulated β-catenin signaling in osteoblasts by bone marrow macrophages
Bone marrow macrophages (BMMs), in the presence of cyclooxygenase-2 (Cox2) produced PGE(2), secrete an inhibitory factor in response to Rankl that blocks PTH-stimulated osteoblastic differentiation. This study was to determine if the inhibitory factor also blocks PTH-stimulated Wnt signaling. Primar...
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| Published in: | Bone |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835216/ https://ncbi.nlm.nih.gov/pubmed/26851123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.01.023 |
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