Serum Amyloid A3 Secreted by Preosteoclasts Inhibits Parathyroid Hormone-stimulated cAMP Signaling in Murine Osteoblasts

Continuous parathyroid hormone (PTH) blocks its own osteogenic actions in marrow stromal cell cultures by inducing Cox2 and receptor activator of nuclear factor κB ligand (RANKL) in the osteoblastic lineage cells, which then cause the hematopoietic lineage cells to secrete an inhibitor of PTH-stimul...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Choudhary, Shilpa, Goetjen, Alexandra, Estus, Thomas, Jacome-Galarza, Christian E., Aguila, Hector L., Lorenzo, Joseph, Pilbeam, Carol
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759168/
https://ncbi.nlm.nih.gov/pubmed/26703472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.686576
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