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Parathyroid Hormone Induction of Cyclooxygenase-2 in Murine Osteoblasts: Role of the Calcium-Calcineurin-NFAT Pathway

Murine MC3T3-E1 and MC-4 cells were stably transfected with −371/+70 bp of the murine cyclooxygenase-2 (COX-2) promoter fused to a luciferase reporter (Pluc371) or with Pluc371 carrying site-directed mutations. Mutations were made in (1) the cAMP response element (CRE) at −57/−52 bp, (2) the activat...

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Detalhes bibliográficos
Main Authors: Huang, Hechang, Chikazu, Daichi, Voznesensky, Olga S, Herschman, Harvey R, Kream, Barbara E, Drissi, Hicham, Pilbeam, Carol C
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153333/
https://ncbi.nlm.nih.gov/pubmed/19821778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/jbmr.091019
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