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Cyclooxygenase-2 Suppresses the Anabolic Response to PTH Infusion in Mice

We previously reported that the ability of continuously elevated PTH to stimulate osteoblastic differentiation in bone marrow stromal cell cultures was abrogated by an osteoclastic factor secreted in response to cyclooxygenase-2 (Cox2)-produced prostaglandin E(2). We now examine the impact of Cox2 (...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Choudhary, Shilpa, Canalis, Ernesto, Estus, Thomas, Adams, Douglas, Pilbeam, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363701/
https://ncbi.nlm.nih.gov/pubmed/25781979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120164
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