Cyclooxygenase-2 Suppresses the Anabolic Response to PTH Infusion in Mice

We previously reported that the ability of continuously elevated PTH to stimulate osteoblastic differentiation in bone marrow stromal cell cultures was abrogated by an osteoclastic factor secreted in response to cyclooxygenase-2 (Cox2)-produced prostaglandin E(2). We now examine the impact of Cox2 (...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Choudhary, Shilpa, Canalis, Ernesto, Estus, Thomas, Adams, Douglas, Pilbeam, Carol
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363701/
https://ncbi.nlm.nih.gov/pubmed/25781979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120164
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