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Structural mechanisms underlying activation of TRPV1 channels by pungent compounds in gingers
BACKGROUND AND PURPOSE: Like chili peppers, gingers produce pungent stimuli by a group of vanilloid compounds that activate the nociceptive transient receptor potential vanilloid 1 (TRPV1) ion channel. How these compounds interact with TRPV1 remains unclear. EXPERIMENTAL APPROACH: We used computatio...
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| Vydáno v: | Br J Pharmacol |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6692589/ https://ncbi.nlm.nih.gov/pubmed/31207668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14766 |
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