Carregant...

Structural mechanism underlying capsaicin binding and activation of TRPV1 ion channel

Capsaicin bestows spiciness by activating TRPV1 channel with exquisite potency and selectivity. Capsaicin-bound channel structure was previously resolved by cryo-EM at 4.2-to-4.5 Å resolution, however important details required for mechanistic understandings are unavailable: capsaicin was registered...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Chem Biol
Autors principals: Yang, Fan, Xiao, Xian, Cheng, Wei, Yang, Wei, Yu, Peilin, Song, Zhenzhen, Yarov-Yarovoy, Vladimir, Zheng, Jie
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472570/
https://ncbi.nlm.nih.gov/pubmed/26053297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1835
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!