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Structural mechanisms underlying activation of TRPV1 channels by pungent compounds in gingers
BACKGROUND AND PURPOSE: Like chili peppers, gingers produce pungent stimuli by a group of vanilloid compounds that activate the nociceptive transient receptor potential vanilloid 1 (TRPV1) ion channel. How these compounds interact with TRPV1 remains unclear. EXPERIMENTAL APPROACH: We used computatio...
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| Pubblicato in: | Br J Pharmacol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6692589/ https://ncbi.nlm.nih.gov/pubmed/31207668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14766 |
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