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The conformational wave in capsaicin activation of transient receptor potential vanilloid 1 ion channel
The capsaicin receptor TRPV1 has been intensively studied by cryo-electron microscopy and functional tests. However, though the apo and capsaicin-bound structural models are available, the dynamic process of capsaicin activation remains intangible, largely due to the lack of a capsaicin-induced open...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6056546/ https://ncbi.nlm.nih.gov/pubmed/30038260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05339-6 |
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