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Establishment of serine protease htrA mutants in Helicobacter pylori is associated with secA mutations

Helicobacter pylori plays an essential role in the pathogenesis of gastritis, peptic ulcer disease, and gastric cancer. The serine protease HtrA, an important secreted virulence factor, disrupts the gastric epithelium, which enables H. pylori to transmigrate across the epithelium and inject the onco...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Zawilak-Pawlik, Anna, Zarzecka, Urszula, Żyła-Uklejewicz, Dorota, Lach, Jakub, Strapagiel, Dominik, Tegtmeyer, Nicole, Böhm, Manja, Backert, Steffen, Skorko-Glonek, Joanna
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692382/
https://ncbi.nlm.nih.gov/pubmed/31409845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48030-6
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