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Amino-Terminal Processing of Helicobacter pylori Serine Protease HtrA: Role in Oligomerization and Activity Regulation

The HtrA family of serine proteases is found in most bacteria, and plays an essential role in the virulence of the gastric pathogen Helicobacter pylori. Secreted H. pylori HtrA (HtrA(Hp)) cleaves various junctional proteins such as E-cadherin disrupting the epithelial barrier, which is crucial for b...

詳細記述

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書誌詳細
出版年:Front Microbiol
主要な著者: Albrecht, Nicole, Tegtmeyer, Nicole, Sticht, Heinrich, Skórko-Glonek, Joanna, Backert, Steffen
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911493/
https://ncbi.nlm.nih.gov/pubmed/29713313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00642
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