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Amino-Terminal Processing of Helicobacter pylori Serine Protease HtrA: Role in Oligomerization and Activity Regulation

The HtrA family of serine proteases is found in most bacteria, and plays an essential role in the virulence of the gastric pathogen Helicobacter pylori. Secreted H. pylori HtrA (HtrA(Hp)) cleaves various junctional proteins such as E-cadherin disrupting the epithelial barrier, which is crucial for b...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Albrecht, Nicole, Tegtmeyer, Nicole, Sticht, Heinrich, Skórko-Glonek, Joanna, Backert, Steffen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911493/
https://ncbi.nlm.nih.gov/pubmed/29713313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00642
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