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Establishment of serine protease htrA mutants in Helicobacter pylori is associated with secA mutations

Helicobacter pylori plays an essential role in the pathogenesis of gastritis, peptic ulcer disease, and gastric cancer. The serine protease HtrA, an important secreted virulence factor, disrupts the gastric epithelium, which enables H. pylori to transmigrate across the epithelium and inject the onco...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zawilak-Pawlik, Anna, Zarzecka, Urszula, Żyła-Uklejewicz, Dorota, Lach, Jakub, Strapagiel, Dominik, Tegtmeyer, Nicole, Böhm, Manja, Backert, Steffen, Skorko-Glonek, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692382/
https://ncbi.nlm.nih.gov/pubmed/31409845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48030-6
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