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The multiple roles of the unfolded protein response regulator IRE1α in cancer
Cancer is associated with a number of conditions such as hypoxia, nutrient deprivation, cellular redox, and pH changes that result in accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) and trigger a stress response known as the unfolded protein response (UPR). The UPR i...
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| Publicado no: | Mol Carcinog |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6692187/ https://ncbi.nlm.nih.gov/pubmed/31041814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.23031 |
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