Chargement en cours...
Dynamic change of electrostatic field in TMEM16F permeation pathway shifts its ion selectivity
TMEM16F is activated by elevated intracellular Ca(2+), and functions as a small-conductance ion channel and as a phospholipid scramblase. In contrast to its paralogs, the TMEM16A/B calcium-activated chloride channels, mouse TMEM16F has been reported as a cation-, anion-, or non-selective ion channel...
Enregistré dans:
| Publié dans: | eLife |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2019
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6690719/ https://ncbi.nlm.nih.gov/pubmed/31318330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45187 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|