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Chemically induced vesiculation as a platform for studying TMEM16F activity

Calcium-activated phospholipid scramblase mediates the energy-independent bidirectional translocation of lipids across the bilayer, leading to transient or, in the case of apoptotic scrambling, sustained collapse of membrane asymmetry. Cells lacking TMEM16F-dependent lipid scrambling activity are de...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Han, Tina W., Ye, Wenlei, Bethel, Neville P., Zubia, Mario, Kim, Andrew, Li, Kathy H., Burlingame, Alma L., Grabe, Michael, Jan, Yuh Nung, Jan, Lily Y.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347726/
https://ncbi.nlm.nih.gov/pubmed/30622179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817498116
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