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TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdala

TMEM16B (ANO2) is the Ca(2+)-activated chloride channel expressed in multiple brain regions, including the amygdala. Here we report that Ano2 knockout mice exhibit impaired anxiety-related behaviors and context-independent fear memory, thus implicating TMEM16B in anxiety modulation. We found that TM...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Li, Ke-Xin, He, Mu, Ye, Wenlei, Simms, Jeffrey, Gill, Michael, Xiang, Xuaner, Jan, Yuh Nung, Jan, Lily Yeh
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746550/
https://ncbi.nlm.nih.gov/pubmed/31482844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47106
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