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ER responses play a key role in Swiss-Cheese/Neuropathy Target Esterase-associated neurodegeneration

Swiss Cheese (SWS) is the Drosophila orthologue of Neuropathy Target Esterase (NTE), a phospholipase that when mutated has been shown to cause a spectrum of disorders in humans that range from intellectual disabilities to ataxia. Loss of SWS in Drosophila also causes locomotion deficits, age-depende...

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Bibliographic Details
Published in:Neurobiol Dis
Main Authors: Sunderhaus, Elizabeth R., Law, Alexander D, Kretzschmar, Doris
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690343/
https://ncbi.nlm.nih.gov/pubmed/31233884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.104520
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