Swiss Cheese, a Protein Involved in Progressive Neurodegeneration, Acts as a Noncanonical Regulatory Subunit for PKA-C3

The Drosophila Swiss Cheese (SWS) protein and its vertebrate ortholog Neuropathy Target Esterase (NTE) are required for neuronal survival and glial integrity. In humans, NTE is the target of organophosphorous compounds which cause a paralyzing axonal degeneration and recently mutations in NTE have b...

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Bibliographic Details
Main Authors: Bettencourt da Cruz, Alexandre, Wentzell, Jill, Kretzschmar, Doris
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723165/
https://ncbi.nlm.nih.gov/pubmed/18945896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3015-08.2008
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