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Organophosphate-Induced Changes in the PKA Regulatory Function of Swiss Cheese/NTE Lead to Behavioral Deficits and Neurodegeneration

Organophosphate-induced delayed neuropathy (OPIDN) is a Wallerian-type axonopathy that occurs weeks after exposure to certain organophosphates (OPs). OPs have been shown to bind to Neuropathy Target Esterase (NTE), thereby inhibiting its enzymatic activity. However, only OPs that also induce the so-...

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Detalhes bibliográficos
Main Authors: Wentzell, Jill S., Cassar, Marlène, Kretzschmar, Doris
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928115/
https://ncbi.nlm.nih.gov/pubmed/24558370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087526
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