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Natural Product MDM2 Inhibitors: Anticancer Activity and Mechanisms of Action

The mdm2 oncogene has recently been suggested to be a valuable target for cancer therapy and prevention. Overexpression of mdm2 is often seen in various human cancers and correlates with high-grade, late-stage, and more treatment-resistant tumors. The MDM2-p53 auto-regulatory loop has been extensive...

詳細記述

保存先:
書誌詳細
出版年:Curr Med Chem
主要な著者: Qin, J.-J., Nag, S., Voruganti, S., Wang, W., Zhang, R.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690201/
https://ncbi.nlm.nih.gov/pubmed/22830335
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