Targeting MDM2 for Neuroblastoma Therapy: In Vitro and In Vivo Anticancer Activity and Mechanism of Action

SIMPLE SUMMARY: Neuroblastoma is a malignant tumor of the sympathetic nervous system that causes aggressive disease in children. The overall survival rate of high-risk patients is very low, therefore developing effective and safe therapies for neuroblastoma is an urgent unmet medical need. The mouse...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Wang, Wei, Wang, Xinjie, Rajaei, Mehrdad, Youn, Ji Youn, Zafar, Atif, Deokar, Hemantkumar, Buolamwini, John K., Yang, Jianhua, Foster, Jennifer H., Zhou, Jia, Zhang, Ruiwen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762001/
https://ncbi.nlm.nih.gov/pubmed/33291373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123651
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