FBA-TPQ, a novel marine-derived compound as experimental therapy for prostate cancer

We recently synthesized a series of novel makaluvamine compounds, and found that the most potent was FBA-TPQ. The effects of FBA-TPQ on human (LNCaP and PC3) and murine (TRAMP Cl) prostate cancer cells were evaluated. Potential mechanisms of action of the compound were also determined. FBA-TPQ exhib...

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Veröffentlicht in:Invest New Drugs
Hauptverfasser: Wang, Feng, Ezell, Scharri J., Zhang, Yong, Wang, Wei, Rayburn, Elizabeth R., Nadkarni, Dwayaja H., Murugesan, Srinivasan, Velu, Sadanandan E., Zhang, Ruiwen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690195/
https://ncbi.nlm.nih.gov/pubmed/19274441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-009-9232-x
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