A novel synthetic iminoquinone, BA-TPQ, as an anti-breast cancer agent: in vitro and in vivo activity and mechanisms of action

Herein we report our examination of the anti-breast cancer activity of a novel synthetic compound, 7-(benzylamino)-1, 3, 4, 8-tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one (BA-TPQ). This agent is an analog of a naturally-occurring marine compound, and was found to be the most active out of more t...

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Detalhes bibliográficos
Main Authors: Wang, Wei, Rayburn, Elizabeth R., Velu, Sadanandan E., Chen, Deng, Nadkarni, Dwayaja H., Murugesan, Srinivasan, Chen, Dongquan, Zhang, Ruiwen
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769174/
https://ncbi.nlm.nih.gov/pubmed/19936915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-009-0638-0
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