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In Vitro and In Vivo Anti-cancer Activity of Novel Synthetic Makaluvamine Analogs
PURPOSE: The present study was designed to determine biological structure-activity relationships (SAR) for four newly synthesized analogs of natural compounds (makaluvamines). The compounds, 7-(4-fluorobenzylamino)-1,3,4,8-tetrahydropyrrolo[4,3,2-de]quinolin-8(1H)-one (FBA-TPQ); 7-(phenethylamino)-1...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3769181/ https://ncbi.nlm.nih.gov/pubmed/19451594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2689 |
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