In Vitro and In Vivo Anti-cancer Activity of Novel Synthetic Makaluvamine Analogs

PURPOSE: The present study was designed to determine biological structure-activity relationships (SAR) for four newly synthesized analogs of natural compounds (makaluvamines). The compounds, 7-(4-fluorobenzylamino)-1,3,4,8-tetrahydropyrrolo[4,3,2-de]quinolin-8(1H)-one (FBA-TPQ); 7-(phenethylamino)-1...

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Detalhes bibliográficos
Main Authors: Wang, Wei, Rayburn, Elizabeth R., Velu, Sadanandan E., Nadkarni, Dwayaja H., Murugesan, Srinivasan, Zhang, Ruiwen
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769181/
https://ncbi.nlm.nih.gov/pubmed/19451594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2689
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