Development and Validation of a HPLC Method for Quantitation of BA-TPQ, a Novel Iminoquinone Anticancer Agent, and an Initial Pharmacokinetic Study in Mice

We herein describe the development and validation of a high performance liquid chromatography (HPLC) method for the quantitation of 7-(benzylamino)-1, 3, 4, 8-tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one (BA-TPQ), a newly synthesized iminoquinone anticancer agent. BA-TPQ was extracted from plasm...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Haibo, Ezell, Scharri J., Zhang, Xiangrong, Wang, Wei, Xu, Hongxia, Rayburn, Elizabeth R., Zhang, Xu, Gurpinar, Evrim, Yang, Xinyi, Sommers, Charnell I., Velu, Sadanandan E., Zhang, Ruiwen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769168/
https://ncbi.nlm.nih.gov/pubmed/20845374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.1498
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