Identification of the ZAK-MKK4-JNK-TGFβ Signaling Pathway as a Molecular Target for Novel Synthetic Iminoquinone Anticancer Compound BA-TPQ

Identification and validation of molecular targets are considered as key elements in new drug discovery and development. We have recently demonstrated that a novel synthetic iminoquinone analog, termed [7-(benzylamino)-1,3,4,8-tetrahydropyrrolo [4,3, 2-de]quinolin-8(1H)-one] (BA-TPQ), has significan...

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Publicado no:Curr Cancer Drug Targets
Principais autores: Chen, Deng, Wang, Wei, Qin, Jiang-Jiang, Wang, Ming-Hai, Murugesan, Srinivasan, Nadkarni, Dwayaja H., Velu, Sadanandan E., Wang, Hui, Zhang, Ruiwen
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705132/
https://ncbi.nlm.nih.gov/pubmed/23607596
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