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Synthesis and In Vitro Anti-Lung Cancer Activity of Novel 1, 3, 4, 8-Tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one Alkaloid Analogs

The high mortality rate and lack of effective therapies make lung cancer an ideal target for novel therapeutic agents. The present study was designed to implement a novel chemical synthesis pathway and to determine the biological activities of synthetic makaluvamine analogs in human lung cancer. Sev...

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Bibliografske podrobnosti
izdano v:Med Chem
Main Authors: Nadkarni, Dwayaja H., Wang, Feng, Wang, Wei, Rayburn, Elizabeth R., Ezell, Scharri J., Murugesan, Srinivasan, Velu, Sadanandan E., Zhang, Ruiwen
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690190/
https://ncbi.nlm.nih.gov/pubmed/19442212
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