Wordt geladen...
UBC9 mutant reveals the impact of protein dynamics on substrate selectivity and SUMO chain linkages
SUMO, a conserved ubiquitin-like protein, is conjugated to a multitude of cellular proteins to maintain genomic integrity and resist genotoxic stress. Studies of the SUMO E2 conjugating enzyme mutant, UBC9(P123L), suggested that altered substrate specificity enhances cell sensitivity to DNA damaging...
Bewaard in:
| Gepubliceerd in: | Biochemistry |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6690184/ https://ncbi.nlm.nih.gov/pubmed/30574775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01045 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|