Site-specific inhibition of the small ubiquitin-like modifier (SUMO)-conjugating enzyme Ubc9 selectively impairs SUMO chain formation

Posttranslational modifications by small ubiquitin-like modifiers (SUMOs) regulate many cellular processes, including genome integrity, gene expression, and ribosome biogenesis. The E2-conjugating enzyme Ubc9 catalyzes the conjugation of SUMOs to ϵ-amino groups of lysine residues in target proteins....

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Wiechmann, Svenja, Gärtner, Anne, Kniss, Andreas, Stengl, Andreas, Behrends, Christian, Rogov, Vladimir V., Rodriguez, Manuel S., Dötsch, Volker, Müller, Stefan, Ernst, Andreas
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2017
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602394/
https://ncbi.nlm.nih.gov/pubmed/28784659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.794255
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk