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The pharmacokinetics of lopinavir/ritonavir when given with isoniazid in South African HIV-infected individuals.
Isoniazid preventive therapy is recommended in patients on antiretroviral therapy with latent tuberculosis infection to prevent progression to active tuberculosis disease. Isoniazid inhibits CYP3A4, which metabolizes lopinavir. Administration of isoniazid may cause higher lopinavir concentrations wh...
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| Udgivet i: | Int J Tuberc Lung Dis |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6689656/ https://ncbi.nlm.nih.gov/pubmed/26459532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5588/ijtld.15.0044 |
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