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Resting State Structure and Gating Mechanism of a Voltage-gated Sodium Channel
Voltage-gated sodium (Na(V)) channels initiate action potentials in nerve, muscle, and other electrically excitable cells. The structural basis of voltage gating is uncertain because the resting state exists only at deeply negative membrane potentials. To stabilize the resting conformation, we inser...
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| Pubblicato in: | Cell |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6688928/ https://ncbi.nlm.nih.gov/pubmed/31353218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.06.031 |
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