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A gene based approach to test genetic association based on an optimally weighted combination of multiple traits

There is increasing evidence showing that pleiotropy is a widespread phenomenon in complex diseases for which multiple correlated traits are often measured. Joint analysis of multiple traits could increase statistical power by aggregating multiple weak effects. Existing methods for multiple trait as...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Zhang, Jianjun, Sha, Qiuying, Liu, Guanfu, Wang, Xuexia
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688794/
https://ncbi.nlm.nih.gov/pubmed/31398229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220914
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