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Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium

Haematopoietic stem cells are generated from the haemogenic endothelium (HE) located in the floor of the dorsal aorta (DA). Despite being integral to arteries, it is controversial whether HE and arterial endothelium share a common lineage. Here, we present a transgenic zebrafish runx1 reporter line...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Bonkhofer, Florian, Rispoli, Rossella, Pinheiro, Philip, Krecsmarik, Monika, Schneider-Swales, Janina, Tsang, Ingrid Ho Ching, de Bruijn, Marella, Monteiro, Rui, Peterkin, Tessa, Patient, Roger
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687740/
https://ncbi.nlm.nih.gov/pubmed/31395869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11423-2
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