BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors

PURPOSE: Breast cancer (BC) risk prediction allows systematic identification of individuals at highest and lowest risk. We extend the Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) risk model to incorporate the effects of polygenic risk scores (PRS) and...

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Publicado en:Genet Med
Autores principales: Lee, Andrew, Mavaddat, Nasim, Wilcox, Amber N., Cunningham, Alex P., Carver, Tim, Hartley, Simon, Babb de Villiers, Chantal, Izquierdo, Angel, Simard, Jacques, Schmidt, Marjanka K., Walter, Fiona M., Chatterjee, Nilanjan, Garcia-Closas, Montserrat, Tischkowitz, Marc, Pharoah, Paul, Easton, Douglas F., Antoniou, Antonis C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group US 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687499/
https://ncbi.nlm.nih.gov/pubmed/30643217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41436-018-0406-9
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