Comparative validation of the BOADICEA and Tyrer-Cuzick breast cancer risk models incorporating classical risk factors and polygenic risk in a population-based prospective cohort of women of European ancestry

BACKGROUND: The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) and the Tyrer-Cuzick breast cancer risk prediction models are commonly used in clinical practice and have recently been extended to include polygenic risk scores (PRS). In addition, BOADICEA...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Pal Choudhury, Parichoy, Brook, Mark N., Hurson, Amber N., Lee, Andrew, Mulder, Charlotta V., Coulson, Penny, Schoemaker, Minouk J., Jones, Michael E., Swerdlow, Anthony J., Chatterjee, Nilanjan, Antoniou, Antonis C., Garcia-Closas, Montserrat
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885342/
https://ncbi.nlm.nih.gov/pubmed/33588869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-021-01399-7
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