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The host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole

To colonize phagocytes, Leishmania subverts microbicidal processes through components of its surface coat that include lipophosphoglycan and the GP63 metalloprotease. How these virulence glycoconjugates are shed, exit the parasitophorous vacuole (PV), and traffic within host cells is poorly understo...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Arango Duque, Guillermo, Jardim, Armando, Gagnon, Étienne, Fukuda, Mitsunori, Descoteaux, Albert
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687203/
https://ncbi.nlm.nih.gov/pubmed/31356625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007982
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